Melasma (Chloasma)

What Is It?

Melasma (also called chloasma) is a condition in which areas of the skin become darker than the surrounding skin. Doctors call this hyperpigmentation. It typically occurs on the face, particularly the forehead, cheeks and upper lip. The dark patches often appear on both sides of the face in a nearly identical pattern. The darker-colored patches of skin can be any shade, from tan to deep brown. Rarely, these dark patches may appear on other sun-exposed areas of the body.

Melasma occurs much more often in women than in men, and usually is associated with hormonal changes. That is why the dark patches develop most often during pregnancy, or if a woman is taking hormone replacement therapy (HRT) or oral contraceptives. Melasma during pregnancy is relatively common. Sometimes it is called the "mask of pregnancy." The dark patches typically last until the pregnancy ends. Despite the strong connection to hormones, no one knows exactly what causes the skin discoloration.

Other factors that make it more likely that a person will get melasma include using medications that make you sensitive to the sun (photosensitizing). These can include some cosmetics and medicines used to treat ovarian or thyroid problems. If you are already susceptible to melasma, exposure to the sun increases your risk. For example, women who are pregnant or who take a hormone medication and avoid the sun are less likely to develop melasma than are those who spend a lot of time in the sun.

Symptoms

Darker patches of skin appear on the forehead, temples, cheeks or upper lip. The symptoms are strictly cosmetic you won't feel ill, and the darker skin won't be sore.

Diagnosis

A doctor will diagnose melasma simply by looking at your skin. Your medical history will help to determine any factors that may have caused the disorder.

Your doctor may use a special lamp that gives off ultraviolet light. This allows the doctor to see patterns and depth of skin discoloration more clearly.

Expected Duration

The dark patches typically last until the pregnancy ends or you stop taking the hormonal medications. The patches gradually fade over many months. In some people, the discoloration never entirely disappears.

Prevention

The best way to prevent melasma is to limit skin exposure to the sun. If you go out in the sun, take these preventive measures:

• Wear a hat with a brim to shade and protect your face.
• Apply sun block (such as zinc oxide or titanium dioxide) to vulnerable areas.
• Use sunscreen that protects against both ultraviolet A and ultraviolet B radiation. The sunscreen should have a sun protection factor (SPF) of at least 30.

Treatment

As hormones stabilize, the dark patches of melasma usually fade. Women who develop melasma as a result of pregnancy often see the patches fade months after the baby is born. Women who take oral contraceptives or hormone replacement therapy often see the patches fade once they stop taking the medications.

A few options may help fade or treat dark patches:

• Hydroquinone is a cream that takes pigment out of the skin. It blocks the natural chemical process that leads to the creation of melanin, the substance that makes skin dark.
• Tretinoin is a type of vitamin A that helps to increase the rate at which dead skin cells fall off and new ones appear. This makes the melasma patch fade more quickly as the pigmented cells are shed.
• Azelaic acid cream appears to work by slowing down or stopping the production of pigment, the substance that makes the skin darker.
• Chemical peels are liquid solutions applied to the skin to provide a mild chemical burn, similar to sunburn. Over time, the burned layers peel off, leaving fresh, new skin. Chemical peels vary in strength. Glycolic acid is among the mildest, and therefore has a lower risk of causing scarring or skin discoloration. Chemical peels may be used if melasma does not respond to other treatments.

Some dermatologists use laser therapy to remove the pigmented layer of skin, but this technique is not a routine treatment for melasma.

When To Call A Professional

See your doctor if you develop any unexplained discoloration of the skin. Although melasma does not require treatment, a doctor can distinguish melasma from other skin disorders that may need to be treated.

Prognosis

Much of the discoloration will fade or disappear once hormones stabilize and you stay out of the sun. For people who find the discolorations unsightly, treatment may help to fade stubborn patches. You also can use cosmetics to even out the skin color.

Additional Info

American Academy of Dermatology

P.O. Box 4014

Schaumburg, IL 60168-4014

Phone: (847) 330-0230

Toll-Free: (888) 462-3376

Fax: (847) 330-0050

http://www.aad.org/

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Information Clearinghouse

National Insitutes of Health

1 AMS Circle

Bethesda, MD 20892-3675

Phone: (301) 495-4484

Toll-Free: (877) 226-4267

Fax: (301) 718-6366

TTY: (301) 565-2966

E-Mail: niamsinfo@mail.nih.gov

http://www.niams.nih.gov/